«Garnierite» of the Uralian province of the oxide-silicate nickel ores is multiphase substance and consists of serpentines, chlorites, clay minerals, mica minerals (talc, willemsite, clintonite, phlogopite) and quartz. Composition of the Uralian «garnierite» is rather different from tropic countries «garnierite» (of New Caledonia, Indonesia, Brazil, Columbia and others). In that countries the main compounds of «garnierite» are presented by exogenic minerals – pimelite (nickel saponite), nepouite, sepiolite, smectite, whereas the Uralian «garnierite» main compounds are presented by hydrothermal minerals - chryzotiles, pecoraite, clinochlore and talc. It testifies the great hydrothermal alteration of Uralian nickel deposit ultramafic substrate. Apparently, the Ural region oxide-silicate nickel deposits are given by a two-floor structure, where upper exogenic floor has a «background» in the form of lower hydrothermal floor. That fact considerably increases the field of geological prospecting and searching of new oxide-silicate nickel deposits in the Uralian region.